Tom Arnold, MD

Publications
  1. The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research.
  2. Microglia are involved in the protection of memories formed during sleep deprivation.
  3. αVβ8 integrin targeting to prevent posterior capsular opacification (PCO).
  4. Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice.
  5. Enrichment of Vascular Fragments from Mouse Embryonic Brains for Endothelial Cell Analysis.
  6. CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.
  7. Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier.
  8. A new genetic strategy for targeting microglia in development and disease.
  9. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of ß-Catenin Signaling.
  10. Impaired aVß8 and TGFß signaling lead to microglial dysmaturation and neuromotor dysfunction.
  11. Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-ß Signaling in Developing Skin Vasculature.
  12. Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice.
  13. The avß1 integrin plays a critical in vivo role in tissue fibrosis.
  14. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation.
  15. Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking aVß8-TGFß signaling in the brain.
  16. Mesangial cell avß8-integrin regulates glomerular capillary integrity and repair.
  17. Targeting of av integrin identifies a core molecular pathway that regulates fibrosis in several organs.
  18. Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality.
  19. Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-ß-TAK1-dependent mechanism.
  20. Ocean acidification and the loss of phenolic substances in marine plants.
  21. Defective retinal vascular endothelial cell development as a consequence of impaired integrin aVß8-mediated activation of transforming growth factor-ß.
  22. Analysis of genomewide association signals for nonsyndromic cleft lip/palate in a Kenya African Cohort.
  23. From death to recovery following hypoxia ischemia: if TGFbeta is a central regulator, is integrin beta8 the switch?
  24. Distribution of orofacial clefts and frequent occurrence of an unusual cleft variant in the Rift Valley of Kenya.