Emily von Scheven, MD, MAS

My long-term goal is to improve the care and outcomes of children with rheumatic diseases. My research has focused on defining and improving outcomes in pediatric-onset Lupus, evaluating and treating childhood osteoporosis and addressing the transition needs of patients as they transition from pediatric to adult providers. I have experience conducting single-center and multi-center studies of various designs, including cohort studies, RCTs, focus groups, and consensus work.
Education
Master's of Advanced Studies, 2004 - Epidemiology & Biostatistics, UCSF
Fellowship, 1995 - Pediatric Rheumatology, Children's Hospital of Philadelphia
Residency, 1992 - Pediatrics, Children's National Medical Center
M.D., 1989 - School of Medicine, Pennsylvania State University
Websites

  1. Weiss PF, Fuhlbrigge RC, von Scheven E, Lovell DJ, Colbert RA, Brunner HI, PRCSG Advisory Council, the CARRA Executive Committee. Children with enthesitis-related arthritis could benefit from treatments targeted for adults with spondyloarthritis. Arthritis care & research 2020. PMID: 33278336


  2. Fawole OA, Reed MV, Harris JG, Hersh A, Rodriguez M, Onel K, Lawson E, Rubinstein T, Ardalan K, Morgan E, Paul A, Barlin J, Daly RP, Dave M, Malloy S, Hume S, Schrandt S, Marrow L, Chapson A, Napoli D, Napoli M, Moyer M, Delgaizo V, Danguecan A, von Scheven E, Knight A, CARRA Investigators. Engaging patients and parents to improve mental health intervention for youth with rheumatological disease. Pediatric rheumatology online journal 2021. PMID: 33622346


  3. von Scheven E, Nahal BK, Cohen IC, Kelekian R, Franck LS. Research Questions that Matter to Us: priorities of young people with chronic illnesses and their caregivers. Pediatric research 2020. PMID: 33069165


  4. Brunner HI, Schanberg LE, Kimura Y, Dennos A, Co DO, Colbert RA, Fuhlbrigge RC, Goldmuntz E, Kingsbury DJ, Patty-Resk C, Mintz S, Onel K, Rider LG, Schneider R, Watts A, von Scheven E, Lovell DJ, Beukelman T, PRCSG Advisory Council and the CARRA Registry Investigators. New Medications Are Needed for Children With Juvenile Idiopathic Arthritis. Arthritis & rheumatology (Hoboken, N.J.) 2020. PMID: 32524767


  5. Mann CM, Schanberg LE, Wang M, von Scheven E, Lucas N, Hernandez A, Ringold S, Reeve BB. Identifying clinically meaningful severity categories for PROMIS pediatric measures of anxiety, mobility, fatigue, and depressive symptoms in juvenile idiopathic arthritis and childhood-onset systemic lupus erythematosus. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2020. PMID: 32410143


  6. Zisman D, Samad A, Ardoin SP, Chira P, White P, Lavi I, von Scheven E, Lawson EF, Hing M, Mellins ED. US Adult Rheumatologists' Perspectives on the Transition Process for Young Adults With Rheumatic Conditions. Arthritis care & research 2020. PMID: 30740937


  7. Rubinstein TB, Ogbu EA, Rodriguez M, Waqar L, Woo JMP, Davis AM, Lapin WB, Ng L, Treemarcki E, von Scheven E, Knight AM, CARRA Mental Health Workgroup. Prioritized Agenda for Mental Health Research in Pediatric Rheumatology from the Childhood Arthritis and Rheumatology Research Alliance Mental Health Workgroup. The Journal of rheumatology 2020. PMID: 31941805


  8. Dumaine C, Bekkar S, Belot A, Cabrera N, Malik S, von Scheven A, Carbasse A, Woerner A, Wouters C, Bouayed K, Pillet P, Schroeder S, Hofer M, Hentgen V. Infectious adverse events in children with Juvenile Idiopathic Arthritis treated with Biological Agents in a real-life setting: Data from the JIRcohorte. Joint bone spine 2019. PMID: 31369865


  9. Shimada H, Dong A, Matsushima-Hibiya Y, Ishimura Y, Caughey WS. Distal His----Arg mutation in bovine myoglobin results in a ligand binding site similar to the abnormal beta site of hemoglobin Zurich (beta 63 His----Arg). Biochemical and biophysical research communications 1989. PMID: 30768778


  10. Heshin-Bekenstein M, Trupin L, Yelin E, von Scheven E, Yazdany J, Lawson EF. Longitudinal disease- and steroid-related damage among adults with childhood-onset systemic lupus erythematosus. Seminars in arthritis and rheumatism 2019. PMID: 31235075


  11. Knight A, Vickery M, Faust L, Muscal E, Davis A, Harris J, Hersh AO, Rodriguez M, Onel K, Rubinstein T, Washington N, Weitzman ER, Conlon H, Woo JMP, Gerstbacher D, von Scheven E, Childhood Arthritis and Rheumatology Research Alliance Investigators. Gaps in Mental Health Care for Youth With Rheumatologic Conditions: A Mixed Methods Study of Perspectives From Behavioral Health Providers. Arthritis care & research 2019. PMID: 29953741


  12. Cooper JC, Rouster-Stevens K, Wright TB, Hsu JJ, Klein-Gitelman MS, Ardoin SP, Schanberg LE, Brunner HI, Eberhard BA, Wagner-Weiner L, Mehta J, Haines K, McCurdy DK, Phillips TA, Huang Z, von Scheven E, CARRA registry investigators. Pilot study comparing the childhood arthritis and rheumatology research alliance consensus treatment plans for induction therapy of juvenile proliferative lupus nephritis. Pediatric rheumatology online journal 2018. PMID: 30348175


  13. Neely J, von Scheven E. Autoimmune haemolytic anaemia and autoimmune thrombocytopenia in childhood-onset systemic lupus erythematosus: updates on pathogenesis and treatment. Current opinion in rheumatology 2018. PMID: 29979258


  14. Lovell DJ, Dare JA, Francis-Sedlak M, Ball J, LaMoreaux BD, Von Scheven E, Reinhardt A, Jerath R, Alpan O, Gupta R, Goldsmith D, Zeft A, Naddaf H, Gottlieb B, Jung L, Holt RJ. A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis. Pediatric rheumatology online journal 2018. PMID: 29941047


  15. Heshin-Bekenstein M, Perl L, Hersh AO, von Scheven E, Yelin E, Trupin L, Yazdany J, Lawson EF. Final adult height of patients with childhood-onset systemic lupus erythematosus: a cross sectional analysis. Pediatric rheumatology online journal 2018. PMID: 29688869


  16. Ling N, Lawson E, von Scheven E. Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate. Pediatric rheumatology online journal 2018. PMID: 29661199


  17. Ringold S, Nigrovic PA, Feldman BM, Tomlinson GA, von Scheven E, Wallace CA, Huber AM, Schanberg LE, Li SC, Weiss PF, Fuhlbrigge RC, Morgan EM, Kimura Y. The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis & rheumatology (Hoboken, N.J.) 2018. PMID: 29333701


  18. Bernatsky S, Clarke AE, Zahedi Niaki O, Labrecque J, Schanberg LE, Silverman ED, Hayward K, Imundo L, Brunner HI, Haines KA, Cron RQ, Oen K, Wagner-Weiner L, Rosenberg AM, O'Neil KM, Duffy CM, von Scheven E, Joseph L, Lee JL, Ramsey-Goldman R. Malignancy in Pediatric-onset Systemic Lupus Erythematosus. The Journal of rheumatology 2017. PMID: 28765255


  19. Boneparth A, Wenderfer SE, Moorthy LN, Radhakrishna SM, Sagcal-Gironella AC, von Scheven E, CARRA Registry investigators. Clinical characteristics of children with membranous lupus nephritis: the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. Lupus 2016. PMID: 27510603


  20. Zahedi Niaki O, Clarke AE, Ramsey-Goldman R, Yeung R, Hayward K, Oen K, Duffy CM, Rosenberg A, O'Neil KM, von Scheven E, Schanberg L, Labrecque J, Tse SM, Hasija R, Lee JL, Bernatsky S. Malignancy incidence in 5294 patients with juvenile arthritis. RMD open 2016. PMID: 27175293


  21. Knight AM, Vickery ME, Muscal E, Davis AM, Harris JG, Soybilgic A, Onel KB, Schanberg LE, Rubinstein T, Gottlieb BS, Mandell DS, von Scheven E, CARRA Investigators. Identifying Targets for Improving Mental Healthcare of Adolescents with Systemic Lupus Erythematosus: Perspectives from Pediatric Rheumatology Clinicians in the United States and Canada. The Journal of rheumatology 2016. PMID: 27036378


  22. Wenderfer SE, Lane JC, Shatat IF, von Scheven E, Ruth NM. Practice patterns and approach to kidney biopsy in lupus: a collaboration of the Midwest Pediatric Nephrology Consortium and the Childhood Arthritis and Rheumatology Research Alliance. Pediatric rheumatology online journal 2015. PMID: 26087651


  23. von Scheven E, Corbin KJ, Stagi S, Stefano S, Cimaz R. Glucocorticoid-associated osteoporosis in chronic inflammatory diseases: epidemiology, mechanisms, diagnosis, and treatment. Current osteoporosis reports 2014. PMID: 25001898


  24. Lawson EF, Hersh AO, Trupin L, von Scheven E, Okumura MJ, Yazdany J, Yelin EH. Educational and vocational outcomes of adults with childhood- and adult-onset systemic lupus erythematosus: nine years of followup. Arthritis care & research 2014. PMID: 24877200


  25. Kraus V, Lawson EF, von Scheven E, Tihan T, Garza J, Nathan RG, Cordoro KM, Waubant E. Atypical cases of scleroderma en coup de sabre. Journal of child neurology 2014. PMID: 24667737


  26. Ardoin SP, Schanberg LE, Sandborg CI, Barnhart HX, Evans GW, Yow E, Mieszkalski KL, Ilowite NT, Eberhard A, Imundo LF, Kimura Y, Levy D, von Scheven E, Silverman E, Bowyer SL, Punaro L, Singer NG, Sherry DD, McCurdy DK, Klein-Gitelman M, Wallace C, Silver RM, Wagner-Weiner L, Higgins GC, Brunner HI, Jung L, Soep JB, Reed AM, Thompson SD, APPLE investigators. Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein. Annals of the rheumatic diseases 2013. PMID: 23436914


  27. Bernatsky S, Clarke AE, Labrecque J, von Scheven E, Schanberg LE, Silverman ED, Brunner HI, Haines KA, Cron RQ, O'Neil KM, Oen K, Rosenberg AM, Duffy CM, Joseph L, Lee JL, Kale M, Turnbull EM, Ramsey-Goldman R. Cancer risk in childhood-onset systemic lupus. Arthritis research & therapy 2013. PMID: 24267155


  28. Applebaum MA, Lawson EF, von Scheven E. Perception of transition readiness and preferences for use of technology in transition programs: teens' ideas for the future. International journal of adolescent medicine and health 2013. PMID: 23740658


  29. Mina R, Klein-Gitelman MS, Ravelli A, Beresford MW, Avcin T, Espada G, Eberhard BA, Schanberg LE, O'Neil KM, Silva CA, Higgins GC, Onel K, Singer NG, von Scheven E, Imundo LF, Nelson S, Giannini EH, Brunner HI. Inactive disease and remission in childhood-onset systemic lupus erythematosus. Arthritis care & research 2012. PMID: 22238253


  30. Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN, Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chédeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI, Carra SLE Subcommittee. Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus. Arthritis care & research 2012. PMID: 22162255


  31. Schanberg LE, Sandborg C, Barnhart HX, Ardoin SP, Yow E, Evans GW, Mieszkalski KL, Ilowite NT, Eberhard A, Imundo LF, Kimura Y, von Scheven E, Silverman E, Bowyer SL, Punaro M, Singer NG, Sherry DD, McCurdy D, Klein-Gitelman M, Wallace C, Silver R, Wagner-Weiner L, Higgins GC, Brunner HI, Jung L, Soep JB, Reed AM, Provenzale J, Thompson SD, Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators. Use of atorvastatin in systemic lupus erythematosus in children and adolescents. Arthritis and rheumatism 2012. PMID: 22031171


  32. Lawson EF, Hersh AO, Applebaum MA, Yelin EH, Okumura MJ, von Scheven E. Self-management skills in adolescents with chronic rheumatic disease: A cross-sectional survey. Pediatric rheumatology online journal 2011. PMID: 22145642


  33. Brunner HI, Mina R, Pilkington C, Beresford MW, Reiff A, Levy DM, Tucker LB, Eberhard BA, Ravelli A, Schanberg LE, Saad-Magalhaes C, Higgins GC, Onel K, Singer NG, von Scheven E, Itert L, Klein-Gitelman MS, Punaro M, Ying J, Giannini EH. Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus. Arthritis care & research 2011. PMID: 21618452


  34. Hersh A, von Scheven E, Yelin E. Adult outcomes of childhood-onset rheumatic diseases. Nature reviews. Rheumatology 2011. PMID: 21487383


  35. von Scheven E, Burnham JM. Vitamin D supplementation in the pediatric rheumatology clinic. Current rheumatology reports 2011. PMID: 21221865


  36. Baker-LePain JC, Nakamura MC, Shepherd J, von Scheven E. Assessment of bone remodelling in childhood-onset systemic lupus erythematosus. Rheumatology (Oxford, England) 2010. PMID: 21098573


  37. Ardoin SP, Schanberg LE, Sandborg C, Yow E, Barnhart HX, Mieszkalski Kl, Ilowite NT, von Scheven E, Eberhard A, Levy DM, Kimura Y, Silverman E, Bowyer SL, Punaro L, Singer NG, Sherry DD, McCurdy D, Klein-Gitelman M, Wallace C, Silver R, Wagner-Weiner L, Higgins GC, Brunner HI, Jung LK, Imundo L, Soep JB, Reed AM, APPLE investigators. Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort. Lupus 2010. PMID: 20861207


  38. Brunner HI, Klein-Gitelman MS, Higgins GC, Lapidus SK, Levy DM, Eberhard A, Singer N, Olson JC, Onel K, Punaro M, Schanberg L, von Scheven E, Ying J, Giannini EH. Toward the development of criteria for global flares in juvenile systemic lupus erythematosus. Arthritis care & research 2010. PMID: 20535792


  39. von Scheven E, Bakkaloglu A. What's new in paediatric SLE? Best practice & research. Clinical rheumatology 2009. PMID: 19853834


  40. Modica RF, Thundiyil JG, Chou C, Diab M, Von Scheven E. Teaching musculoskeletal physical diagnosis using a web-based tutorial and pathophysiology-focused cases. Medical education online 2009. PMID: 20165527


  41. Lenders CM, Feldman HA, Von Scheven E, Merewood A, Sweeney C, Wilson DM, Lee PD, Abrams SH, Gitelman SE, Wertz MS, Klish WJ, Taylor GA, Chen TC, Holick MF, Elizabeth Glaser Pediatric Research Network Obesity Study Group. Relation of body fat indexes to vitamin D status and deficiency among obese adolescents. The American journal of clinical nutrition 2009. PMID: 19640956


  42. Hersh AO, Pang S, Curran ML, Milojevic DS, von Scheven E. The challenges of transferring chronic illness patients to adult care: reflections from pediatric and adult rheumatology at a US academic center. Pediatric rheumatology online journal 2009. PMID: 19505332


  43. Schanberg LE, Sandborg C, Barnhart HX, Ardoin SP, Yow E, Evans GW, Mieszkalski KL, Ilowite NT, Eberhard A, Levy DM, Kimura Y, von Scheven E, Silverman E, Bowyer SL, Punaro L, Singer NG, Sherry DD, McCurdy D, Klein-Gitelman M, Wallace C, Silver R, Wagner-Weiner L, Higgins GC, Brunner HI, Jung L, Soep JB, Reed A, Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators. Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort. Arthritis and rheumatism 2009. PMID: 19404953


  44. Hersh AO, von Scheven E, Yazdany J, Panopalis P, Trupin L, Julian L, Katz P, Criswell LA, Yelin E. Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus. Arthritis and rheumatism 2009. PMID: 19116979


  45. von Scheven E. Pediatric bone density and fracture. Current osteoporosis reports 2007. PMID: 17925194


  46. von Scheven E. Does calcium supplementation increase bone mineral density in healthy children? Nature clinical practice. Rheumatology 2007. PMID: 17342080


  47. Modica R, Emery H, Lam W, Hermiston M, Grenert J, Wirt M, von Scheven E. Epstein-Barr virus-associated B cell lymphoproliferative disease in a child with neonatal-onset multisystem inflammatory disease. Arthritis and rheumatism 2006. PMID: 17013844


  48. Harel L, Sandborg C, Lee T, von Scheven E. Neuropsychiatric manifestations in pediatric systemic lupus erythematosus and association with antiphospholipid antibodies. The Journal of rheumatology 2006. PMID: 16845706


  49. von Scheven E, Gordon CM, Wypij D, Wertz M, Gallagher KT, Bachrach L. Variable deficits of bone mineral despite chronic glucocorticoid therapy in pediatric patients with inflammatory diseases: a Glaser Pediatric Research Network study. Journal of pediatric endocrinology & metabolism : JPEM 2006. PMID: 16886590


  50. Kilcline C, Shinkai K, Bree A, Modica R, Von Scheven E, Frieden IJ. Neonatal-onset multisystem inflammatory disorder: the emerging role of pyrin genes in autoinflammatory diseases. Archives of dermatology 2005. PMID: 15724022


  51. von Scheven E, Elder ME. Association between beta2-glycoprotein I gene polymorphisms and pediatric SLE and antiphospholipid antibodies. Lupus 2005. PMID: 16038107


  52. Soep JB, Mietus-Snyder M, Malloy MJ, Witztum JL, von Scheven E. Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus. Arthritis and rheumatism 2004. PMID: 15188333


  53. Fullerton HJ, Von Scheven E. Back to school on APS: rethinking the risk of recurrent stroke in children. Neurology 2004. PMID: 14745047


  54. von Scheven E, Lu TT, Emery HM, Elder ME, Wara DW. Thrombosis and pediatric Wegener's granulomatosis: acquired and genetic risk factors for hypercoagulability. Arthritis and rheumatism 2003. PMID: 14673976


  55. von Scheven E, Glidden DV, Elder ME. Anti-beta2-glycoprotein I antibodies in pediatric systemic lupus erythematosus and antiphospholipid syndrome. Arthritis and rheumatism 2002. PMID: 12209489


  56. Lee T, von Scheven E, Sandborg C. Systemic lupus erythematosus and antiphospholipid syndrome in children and adolescents. Current opinion in rheumatology 2001. PMID: 11604598


  57. von Scheven E, Lee C, Berg BO. Pediatric Wegener's granulomatosis complicated by central nervous system vasculitis. Pediatric neurology 1998. PMID: 9831006


  58. Busch R, Doebele RC, von Scheven E, Fahrni J, Mellins ED. Aberrant intermolecular disulfide bonding in a mutant HLA-DM molecule: implications for assembly, maturation, and function. Journal of immunology (Baltimore, Md. : 1950) 1998. PMID: 9551909


  59. von Scheven E, Athreya BH, Rose CD, Goldsmith DP, Morton L. Clinical characteristics of antiphospholipid antibody syndrome in children. The Journal of pediatrics 1996. PMID: 8804321


  60. Shaman J, von Scheven E, Morris P, Chang MD, Mellins E. Analysis of HLA-DMB mutants and -DMB genomic structure. Immunogenetics 1995. PMID: 7528727


  61. Von Scheven E, Dietzel W. Hygienic problems in anaesthesia and intensive care therapy. Praktische Anasthesie, Wiederbelebung und Intensivtherapie 1976. PMID: 967788


  62. Dietzel W, von Scheven E, Botzenhart K. [Chemical disinfection of anaesthetic equipment (author's transl)]. Praktische Anasthesie, Wiederbelebung und Intensivtherapie 1974. PMID: 4457861